Characterization of 37 breed-specific single-nucleotide polymorphisms in sheep.

نویسندگان

  • Lorraine Pariset
  • Irene Cappuccio
  • Paolo Ajmone-Marsan
  • Michael Bruford
  • Susana Dunner
  • Oscar Cortes
  • Georg Erhardt
  • Eva-Maria Prinzenberg
  • Katja Gutscher
  • Stephane Joost
  • Gabriela Pinto-Juma
  • Isaäc J Nijman
  • Johannes A Lenstra
  • Trinidad Perez
  • Alessio Valentini
چکیده

We identified 37 single-nucleotide polymorphisms (SNPs) in sheep and screened 16 individuals from 8 different sheep breeds selected throughout Europe. Population genetic measures based on the genotyping of about 30 sheep from the same 8 breeds are reported. To date, there are no sheep SNPs documented in the National Center for Biotechnology Information dbSNP database. Therefore, the markers presented here contribute significantly to those currently available.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Single Nucleotide Polymorphisms (SNPs) of GDF9 Gene in Bahmaei and Lak Ghashghaei Sheep Breeds and Its Association with Litter Size

Growth differentiation factor 9 (GDF9) belong to the superfamily of transforming growth factor β that is highly expressed in growing ovarian follicles of oocyte, and it has been strongly related to fecundity traits in sheep. Therefore, the GDF9 gene could serve as a genetic marker for improvement of reproductive performance in sheep. Therefore, the aim of this study was to invest...

متن کامل

Single Nucleotide Polymorphism Analysis of the Bone Morphogenetic Protein Receptor IB and Growth and Differentiation Factor 9 Genes in Rayini Goats (Capra hircus)

The FecB, a mutation in the bone morphogenetic protein receptor IB (BMPR-IB) gene, which increases the fecundity of Booroola Merino sheep, and FecGH, a mutation in the Growth and Differentiation Factor 9 (GDF9), which affects the fecundity of Cambridge and Belclare sheep in a dose sensitive manner, were analyzed as candidate genes associated with the prolificacy in Rayini goats. These polymorph...

متن کامل

Genetic Characterization of Albanian Sheep Breeds by Microsatellite Markers

Albania is a Mediterranean country, located in West of Balkan Peninsula. Albanian farmers have a long tradition in sheep breeding. Sheep comprise one of the most important domestic livestock species in Albania and play an important role in the livelihood of local community since they are a good source of meat, milk and coarse wool (Dobi et al., 2006; Porcu and Markovic, 2005). There are three i...

متن کامل

Polymorphisms of the Ovine Leptin Gene and its Association with Growth and Carcass Traits in Three Iranian Sheep Breeds

Leptin (LEP), the expression product of the obese gene produced primarily in the adipose tissue, is related to feed intake, growth and lipid metabolism. The aim of this study was to study the possible association between polymorphism of the LEP gene with growth and carcass traits among three Iranian sheep breeds of the Shal, Zandi and Zel varieties. A total of 180 purebred animals of the Shal, ...

متن کامل

Association of IGF-I Gene Polymorphisms with Carcass Traits in Iranian Mehraban Sheep Using SSCP Analysis

Molecular genetics selection on individual genes is a promising method to genetically improve economically important traits in livestock. The insulin like growth factor-I (IGF-I) gene may play important roles in growth of multiple tissues, including muscle cells, cartilage and bone. The objectives of the present study were the estimate the haplotype frequencies of the IGF-I gene polymorphisms i...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • The Journal of heredity

دوره 97 5  شماره 

صفحات  -

تاریخ انتشار 2006